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Altay Therapeutics

Altay develops disease-modifying therapies targeting transcription…

Founded
2019
Status
Active
Stage
Early
Team size
6
Location
San Francisco, CA, USA; South San Francisco
Category
Biotech & Drug Discovery
Sector
Therapeutics

About Altay Therapeutics

Altay develops small molecule drugs to treat chronic liver diseases like liver fibrosis and liver cancer. Our co-founder Dr. Osman Ozes, led the first drug development program for Esbriet (Pirfenidone), resulting in the first FDA approved therapy for lung fibrosis. Esbriet is now a $1 billion/year drug and has already made over $6 billion in revenue. With a team that has over 70+ years of small molecule drug development experience, we intend to do the same with chronic liver diseases, which affects over 20 million Americans and represents a market size of over $30 billion. We know we are well positioned for success because we have shown excellent pre-clinical mouse data in several liver fibrosis models using our novel small molecule. We demonstrate a reduction in fibrosis with our drug, but more significantly, we show a reversal in fibrotic tissue back to normal tissue. With our current developmental strategy, we hope to have a clinic-ready compound by the end of 2021 and be in phase I clinical trials by mid of 2022.

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Federal research funding

4 NIH awards totalling $1,298,527, FY2022 to FY2024.

  • The development of a STAT3 inhibitor for lung scleroderma
  • Novel STAT3 inhibitor for overcoming chemoresistant ovarian cancer .
  • The development of a transcriptional inhibitor for lung fibrosis.
  • Development of a direct DUX4 inhibitor for Facioscapulohumeral Muscular Dystrophy (FSHD)

Source: NIH RePORTER.

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