Altay Therapeutics
Altay develops disease-modifying therapies targeting transcription…
- Founded
- 2019
- Status
- Active
- Stage
- Early
- Team size
- 6
- Location
- San Francisco, CA, USA; South San Francisco
- Category
- Biotech & Drug Discovery
- Sector
- Therapeutics
About Altay Therapeutics
Altay develops small molecule drugs to treat chronic liver diseases like liver fibrosis and liver cancer. Our co-founder Dr. Osman Ozes, led the first drug development program for Esbriet (Pirfenidone), resulting in the first FDA approved therapy for lung fibrosis. Esbriet is now a $1 billion/year drug and has already made over $6 billion in revenue. With a team that has over 70+ years of small molecule drug development experience, we intend to do the same with chronic liver diseases, which affects over 20 million Americans and represents a market size of over $30 billion. We know we are well positioned for success because we have shown excellent pre-clinical mouse data in several liver fibrosis models using our novel small molecule. We demonstrate a reduction in fibrosis with our drug, but more significantly, we show a reversal in fibrotic tissue back to normal tissue. With our current developmental strategy, we hope to have a clinic-ready compound by the end of 2021 and be in phase I clinical trials by mid of 2022.
Federal research funding
4 NIH awards totalling $1,298,527, FY2022 to FY2024.
- The development of a STAT3 inhibitor for lung scleroderma
- Novel STAT3 inhibitor for overcoming chemoresistant ovarian cancer .
- The development of a transcriptional inhibitor for lung fibrosis.
- Development of a direct DUX4 inhibitor for Facioscapulohumeral Muscular Dystrophy (FSHD)
Source: NIH RePORTER.
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