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Shasqi

Targeting Cancer with Click Chemistry

Founded
2015
Status
Active
Stage
Growth
Team size
28
Location
San Francisco, CA, USA; Remote
Category
Biotech & Drug Discovery
Sector
Drug Discovery and Delivery

About Shasqi

Shasqi is leading the development of therapeutics leveraging click chemistry to get active cancer treatments to tumors with its proprietary CAPACâ„¢ platform. Our technology is based on localizing a click chemistry reagent in the tumor area, which then activates a second agent, a systemically infused protodrug. When the two 'click', a powerful localized therapy is activated at the tumor, while keeping its systemic exposure levels below toxic thresholds.

BiotechTherapeutics

Clinical trials

1 registered trial with this company as lead sponsor, 2020.

Phases
Phase 1 (1), Phase 2 (1)
Status
Terminated (1)
Conditions
Cancer

NCT04106492

Source: ClinicalTrials.gov.

Federal research funding

10 NIH awards totalling $9,091,553, FY2021 to FY2025.

  • CEACAM5-targeted activation of potent chemotherapeutics via bioorthogonal click chemistry
  • Antigen-targeted activation of Topo1 inhibitors via click chemistry
  • Antibody-guided localized activation of bioorthogonal protodrugs via click chemistry
  • Assessing the safety and efficacy of SQ3370 in a phase 1b dose-expansion cohort at the recommended Phase 2 dos

Source: NIH RePORTER.

Company data compiled and maintained by Healthcare Discovery.