326 Ophthalmology providers practice in South Carolina. The largest concentration is in Charleston. Profiles include federal Open Payments records of money received from drug and device companies in 2025. Listings are drawn from federal public records and are not endorsements.
Choose a city to see providers there.
| Ophthalmology in Charleston | 65 providers |
| Ophthalmology in Greenville | 48 providers |
| Ophthalmology in Columbia | 42 providers |
| Ophthalmology in Myrtle Beach | 11 providers |
| Ophthalmology in Ladson | 10 providers |
| Ophthalmology in Florence | 10 providers |
| Ophthalmology in West Columbia | 8 providers |
| Ophthalmology in Rock Hill | 8 providers |
| Ophthalmology in Anderson | 8 providers |
| Ophthalmology in Lexington | 7 providers |
| Ophthalmology in Mt Pleasant | 7 providers |
| Ophthalmology in Greenwood | 7 providers |
| Ophthalmology in Mount Pleasant | 6 providers |
| Ophthalmology in Boiling Springs | 6 providers |
| Ophthalmology in Spartanburg | 5 providers |
| Ophthalmology in Orangeburg | 5 providers |
| Ophthalmology in Aiken | 5 providers |
| Ophthalmology in Easley | 5 providers |
| Ophthalmology in Bluffton | 5 providers |
| Ophthalmology in Georgetown | 5 providers |
| Ophthalmology in N Charleston | 4 providers |
| Ophthalmology in Murrells Inlet | 4 providers |
| Ophthalmology in Lancaster | 4 providers |
| Ophthalmology in Hilton Head Island | 4 providers |
From CMS Medicare enrollment records covering 206 of the 326 providers listed here (63%). Providers who do not bill Medicare are not included in these figures.
| Group (as registered with Medicare) | Ophthalmologists | All clinicians in group | Main city |
| Clemson Eye PA | 17 | 51 | Greenville |
| University Medical Associates of the Medical University of South Carol | 13 | 1,634 | Charleston |
| Carolina Eyecare Physicians LLC | 13 | 27 | Charleston |
| Columbia Eye Clinic PA | 10 | 20 | Columbia |
| Charleston Neurosciences Institute | 9 | 9 | Charleston |
| Hospital | City | Ownership | CMS star rating | Ophthalmologists affiliated |
| Musc Medical Center | Charleston | Government | 2 of 5 | 19 |
| St Francis-Downtown | Greenville | Nonprofit | 4 of 5 | 9 |
| Prisma Health Richland Hospital | Columbia | Nonprofit | 3 of 5 | 9 |
| Prisma Health Greenville Memorial Hospital | Greenville | Nonprofit | 4 of 5 | 8 |
| Spartanburg Medical Center | Spartanburg | Government | 2 of 5 | 8 |
Sources: CMS Doctors and Clinicians (August 2026) and Facility Affiliation files (August 2026); hospital ownership type and overall star rating from CMS Hospital General Information (July 2026). A clinician in several groups is counted once, in the largest group they bill through. Ownership type is what the hospital reports to CMS; it does not show private equity or other investor ownership. How we build this directory.
Listed by city, largest first. Payment figures come from the federal Open Payments program, which requires drug and device companies to report what they pay physicians for consulting, speaking, meals, travel and royalties. A disclosed payment is a financial relationship, not evidence of wrongdoing, and many totals reflect a single meal. Figures cover calendar year 2025.
Patients often search by condition rather than specialty. These are conditions typically managed by Ophthalmology providers. Individual practices vary, so confirm with the provider before booking.
There are 326 Ophthalmology providers with active NPI records practicing in South Carolina, according to federal NPPES data refreshed monthly.
Charleston (65), Greenville (48), Columbia (42) have the highest concentration of Ophthalmology providers in South Carolina.
222 of 326 Ophthalmology providers in South Carolina (68%) received at least one payment from a drug or device company in 2025, according to the federal Open Payments program.
Ophthalmology providers commonly treat macular degeneration, cataracts, glaucoma, diabetic retinopathy, dry eye and related conditions. Individual practices vary, so confirm with the provider before booking.
Provider counts and profiles come from the federal NPPES registry and CMS Doctors and Clinicians files. Payment figures come from the CMS Open Payments program for calendar year 2025. The directory refreshes monthly.
Among 206 Ophthalmologists in South Carolina enrolled in Medicare, 51% bill through a solo or small practice with fewer than 10 clinicians, 35% through a mid-size group of 10 to 99, and 14% through a large group or health system with 100 or more clinicians, according to CMS enrollment records.
According to CMS facility affiliation records, the South Carolina hospitals where the most Ophthalmologists hold privileges are Musc Medical Center in Charleston; St Francis-Downtown in Greenville; Prisma Health Richland Hospital in Columbia.
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