2,703 Family Medicine providers practice in South Carolina, including 467 (17%) offering telehealth. The largest concentration is in Columbia. Profiles include federal Open Payments records of money received from drug and device companies in 2025. Listings are drawn from federal public records and are not endorsements.
Choose a city to see providers there.
| Family Medicine in Columbia | 237 providers |
| Family Medicine in Greenville | 214 providers |
| Family Medicine in Charleston | 204 providers |
| Family Medicine in Spartanburg | 144 providers |
| Family Medicine in Florence | 136 providers |
| Family Medicine in Anderson | 104 providers |
| Family Medicine in Greenwood | 90 providers |
| Family Medicine in Myrtle Beach | 85 providers |
| Family Medicine in Greer | 67 providers |
| Family Medicine in Seneca | 55 providers |
| Family Medicine in Simpsonville | 53 providers |
| Family Medicine in Summerville | 51 providers |
| Family Medicine in Lexington | 50 providers |
| Family Medicine in Sumter | 48 providers |
| Family Medicine in North Charleston | 44 providers |
| Family Medicine in Rock Hill | 41 providers |
| Family Medicine in West Columbia | 38 providers |
| Family Medicine in Easley | 38 providers |
| Family Medicine in Mt Pleasant | 36 providers |
| Family Medicine in Aiken | 33 providers |
| Family Medicine in Clemson | 26 providers |
| Family Medicine in Manning | 25 providers |
| Family Medicine in Conway | 25 providers |
| Family Medicine in Beaufort | 23 providers |
From CMS Medicare enrollment records covering 1,514 of the 2,703 providers listed here (56%). Providers who do not bill Medicare are not included in these figures.
| Group (as registered with Medicare) | Family Medicine Doctors | All clinicians in group | Main city |
| Prisma Health University Medical Group | 122 | 2,467 | Greenville |
| Spartanburg Medical Center | 108 | 1,060 | Spartanburg |
| Lexington Health Inc. | 93 | 905 | Columbia |
| Roper Saint Francis Physicians Network | 73 | 530 | Charleston |
| Self Medical Group | 61 | 393 | Greenwood |
| Hospital | City | Ownership | CMS star rating | Family Medicine Doctors affiliated |
| Musc Medical Center | Charleston | Government | 2 of 5 | 176 |
| Prisma Health Greenville Memorial Hospital | Greenville | Nonprofit | 4 of 5 | 166 |
| Spartanburg Medical Center | Spartanburg | Government | 2 of 5 | 151 |
| Prisma Health Patewood Hospital | Greenville | Nonprofit | 5 of 5 | 130 |
| Prisma Health Richland Hospital | Columbia | Nonprofit | 3 of 5 | 120 |
Sources: CMS Doctors and Clinicians (August 2026) and Facility Affiliation files (August 2026); hospital ownership type and overall star rating from CMS Hospital General Information (July 2026). A clinician in several groups is counted once, in the largest group they bill through. Ownership type is what the hospital reports to CMS; it does not show private equity or other investor ownership. How we build this directory.
Listed by city, largest first. Payment figures come from the federal Open Payments program, which requires drug and device companies to report what they pay physicians for consulting, speaking, meals, travel and royalties. A disclosed payment is a financial relationship, not evidence of wrongdoing, and many totals reflect a single meal. Figures cover calendar year 2025.
Patients often search by condition rather than specialty. These are conditions typically managed by Family Medicine providers. Individual practices vary, so confirm with the provider before booking.
There are 2,703 Family Medicine providers with active NPI records practicing in South Carolina, according to federal NPPES data refreshed monthly.
Yes. 467 of the 2,703 Family Medicine providers in South Carolina (about 17%) report offering telehealth services in CMS data.
Columbia (237), Greenville (214), Charleston (204) have the highest concentration of Family Medicine providers in South Carolina.
1,361 of 2,703 Family Medicine providers in South Carolina (50%) received at least one payment from a drug or device company in 2025, according to the federal Open Payments program.
Family Medicine providers commonly treat annual physicals, high blood pressure, type 2 diabetes, preventive care, minor injuries and related conditions. Individual practices vary, so confirm with the provider before booking.
Provider counts and profiles come from the federal NPPES registry and CMS Doctors and Clinicians files. Payment figures come from the CMS Open Payments program for calendar year 2025. The directory refreshes monthly.
Among 1,514 Family Medicine Doctors in South Carolina enrolled in Medicare, 13% bill through a solo or small practice with fewer than 10 clinicians, 20% through a mid-size group of 10 to 99, and 67% through a large group or health system with 100 or more clinicians, according to CMS enrollment records.
According to CMS facility affiliation records, the South Carolina hospitals where the most Family Medicine Doctors hold privileges are Musc Medical Center in Charleston; Prisma Health Greenville Memorial Hospital in Greenville; Spartanburg Medical Center in Spartanburg.
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