24 Infectious Disease providers practice in South Dakota, including 16 (67%) offering telehealth. The largest concentration is in Sioux Falls. Profiles include federal Open Payments records of money received from drug and device companies in 2025. Listings are drawn from federal public records and are not endorsements.
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| Infectious Disease in Sioux Falls | 17 providers |
| Infectious Disease in Rapid City | 7 providers |
From CMS Medicare enrollment records covering 15 of the 24 providers listed here (63%). Providers who do not bill Medicare are not included in these figures.
| Group (as registered with Medicare) | Infectious Disease Specialists | All clinicians in group | Main city |
| Avera Mckennan | 7 | 957 | Sioux Falls |
| Sanford Medical Center | 4 | 847 | Sioux Falls |
| Monument Health Rapid City Hospital Inc. | 4 | 560 | Rapid City |
| St Michael's Hospital, Inc.. | 4 | 16 | Tyndall |
| Hospital | City | Ownership | CMS star rating | Infectious Disease Specialists affiliated |
| Avera Mckennan Hospital & University Health Center | Sioux Falls | Nonprofit | 4 of 5 | 7 |
| Monument Health Rapid City Hospital | Rapid City | Nonprofit | 3 of 5 | 4 |
| Sanford Usd Medical Center | Sioux Falls | Nonprofit | 5 of 5 | 4 |
| Avera St Lukes | Aberdeen | Nonprofit | 4 of 5 | 4 |
| Avera Sacred Heart Hospital | Yankton | Nonprofit | 3 of 5 | 4 |
Sources: CMS Doctors and Clinicians (August 2026) and Facility Affiliation files (August 2026); hospital ownership type and overall star rating from CMS Hospital General Information (July 2026). A clinician in several groups is counted once, in the largest group they bill through. Ownership type is what the hospital reports to CMS; it does not show private equity or other investor ownership. How we build this directory.
Listed by city, largest first. Payment figures come from the federal Open Payments program, which requires drug and device companies to report what they pay physicians for consulting, speaking, meals, travel and royalties. A disclosed payment is a financial relationship, not evidence of wrongdoing, and many totals reflect a single meal. Figures cover calendar year 2025.
Patients often search by condition rather than specialty. These are conditions typically managed by Infectious Disease providers. Individual practices vary, so confirm with the provider before booking.
There are 24 Infectious Disease providers with active NPI records practicing in South Dakota, according to federal NPPES data refreshed monthly.
Yes. 16 of the 24 Infectious Disease providers in South Dakota (about 67%) report offering telehealth services in CMS data.
Sioux Falls (17), Rapid City (7) have the highest concentration of Infectious Disease providers in South Dakota.
Infectious Disease providers commonly treat long COVID, HIV care, Lyme disease, recurrent infections, travel medicine and related conditions. Individual practices vary, so confirm with the provider before booking.
Provider counts and profiles come from the federal NPPES registry and CMS Doctors and Clinicians files. Payment figures come from the CMS Open Payments program for calendar year 2025. The directory refreshes monthly.
Among 15 Infectious Disease Specialists in South Dakota enrolled in Medicare, 0% bill through a solo or small practice with fewer than 10 clinicians, 0% through a mid-size group of 10 to 99, and 100% through a large group or health system with 100 or more clinicians, according to CMS enrollment records.
According to CMS facility affiliation records, the South Dakota hospitals where the most Infectious Disease Specialists hold privileges are Avera Mckennan Hospital & University Health Center in Sioux Falls; Monument Health Rapid City Hospital in Rapid City; Sanford Usd Medical Center in Sioux Falls.
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