myDNAge Epigenetic Clock: The Original Horvath Clock Made Consumer-Accessible
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myDNAge Epigenetic Clock: The Original Horvath Clock Made Consumer-Accessible

Built by the epigenetics company behind the gold-standard research reagents, myDNAge brings Steve Horvath’s original epigenetic clock directly to consumers, with the unique option of testing from a urine sample. In 2013, Steve Horvath at UCLA published the paper that launched the field of epigenetic aging. By identifying 353 CpG sites across the human genome…

Chronomics Epigenetic Testing: Longitudinal Biological Age Tracking and Lifestyle Impact Measurement
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Chronomics Epigenetic Testing: Longitudinal Biological Age Tracking and Lifestyle Impact Measurement

Designed for repeat testing rather than one-time snapshots, Chronomics measures biological age through DNA methylation with a focus on tracking how lifestyle changes move the needle over time. The most valuable question in longevity science is not “how old are my cells right now?” but “is what I am doing actually slowing down my aging?”…

GeneSight Pharmacogenomics: How Genetic Testing Is Changing Psychiatric Medication Selection
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GeneSight Pharmacogenomics: How Genetic Testing Is Changing Psychiatric Medication Selection

For the millions of patients who cycle through antidepressant after antidepressant without relief, GeneSight offers a genetic map of how their body metabolizes psychiatric medications. The science of pharmacogenomics is mature. The question is whether this $2,000 test changes outcomes. Approximately one in three patients with major depressive disorder does not respond adequately to their…

Color Health Genetic Testing: Clinical-Grade Hereditary Cancer Screening With Genetic Counseling Included
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Color Health Genetic Testing: Clinical-Grade Hereditary Cancer Screening With Genetic Counseling Included

Unlike consumer genetics services that test a handful of variants, Color screens the full coding regions of genes linked to hereditary cancer and heart disease, with genetic counseling included in every test. For people with family histories, this distinction could be lifesaving. In 2013, Angelina Jolie disclosed that she carried a pathogenic BRCA1 mutation and…

SelfDecode: AI-Powered DNA Analysis and Personalized Health Recommendations From Your Existing Genetic Data
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SelfDecode: AI-Powered DNA Analysis and Personalized Health Recommendations From Your Existing Genetic Data

Upload your existing genetic data from 23andMe or AncestryDNA and unlock over 100 AI-generated health reports with personalized supplement and lifestyle recommendations. But how much clinical weight should you give an algorithm’s interpretation of your SNPs? The global direct-to-consumer genetic testing market has generated tens of millions of genotyped consumers, most of whom received a…

GlycanAge: Measuring Biological Age Through Your Immune System’s Sugar Coating
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GlycanAge: Measuring Biological Age Through Your Immune System’s Sugar Coating

While most biological age tests measure DNA methylation, GlycanAge uses a fundamentally different biomarker: the sugar molecules coating your antibodies. This glycan-based approach reveals immune system aging in a way that epigenetic clocks cannot. Every antibody in your bloodstream carries a coat of sugar molecules called glycans that fundamentally alter how the immune system behaves….

Elysium Index: An Accessible Entry Point to Epigenetic Age Testing
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Elysium Index: An Accessible Entry Point to Epigenetic Age Testing

Backed by Nobel Prize-winning science and priced at $299, the Elysium Index measures biological age through DNA methylation. Is this the most accessible on-ramp to epigenetic health tracking? The concept that aging can be measured, not just experienced, is one of the most consequential ideas in modern longevity science. In 2018, Morgan Levine and Steve…

TruDiagnostic TruAge Complete: Epigenetic Age Testing and the Science of Measuring How Fast You Are Aging
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TruDiagnostic TruAge Complete: Epigenetic Age Testing and the Science of Measuring How Fast You Are Aging

The most comprehensive consumer epigenetic age test on the market measures not just how old your cells appear but how fast they are aging. Does the science of DNA methylation clocks justify the $499 price tag? In 2013, Steve Horvath, a geneticist at UCLA, published a landmark paper that fundamentally changed how scientists think about…

Nebula Genomics: Whole Genome Sequencing, Data Ownership, and the Case for Reading Every Base Pair
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Nebula Genomics: Whole Genome Sequencing, Data Ownership, and the Case for Reading Every Base Pair

While most consumer genetic tests read a fraction of your genome, Nebula sequences all 3.2 billion base pairs and lets you keep the data. Is whole genome sequencing ready for the health-conscious consumer? The human genome contains approximately 3.2 billion base pairs of DNA. When a consumer takes a standard genotyping test from 23andMe or…

AncestryDNA: The World’s Largest Genetic Database and What It Means for Health Discovery
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AncestryDNA: The World’s Largest Genetic Database and What It Means for Health Discovery

With over 20 million people genotyped, AncestryDNA holds the largest consumer genetic database on Earth. But its focus remains firmly on genealogy, not health. Where does this test fit in the genomic landscape? In 2012, a team at Ancestry.com launched a saliva-based DNA test designed not for hospitals or research institutions but for the millions…