A deep dive into neuroinflammageing and the 2025 to 2026 research showing the brain’s resident immune cells, the microglia, drive cognitive aging, and how scientists at Cedars-Sinai, UC Irvine, and…
Almost three decades after Makoto Kuro-o named the protein after the Greek Fate of life, UCSF’s Dena Dubal has launched the first human trial of klotho. Inside the cell biology,…
A new generation of human trials and mechanistic studies is converging on a striking conclusion: resistance training does not merely preserve muscle. It signals the brain. Inside the myokine biology,…
First documented by Makoto Kuro-o in a 1997 Nature paper, the Klotho hormone has spent thirty years quietly accumulating one of the deepest evidence bases in aging biology. With Phase…
Scientists at the Institute for Bioengineering of Catalonia and West China Hospital engineered supramolecular nanoparticles that cleared 50 to 60 percent of amyloid-beta from Alzheimer’s mice within one hour, restored…
In 2013, Maiken Nedergaard’s lab at the University of Rochester discovered that the brain runs a sleep-gated waste clearance network called the glymphatic system. Twelve years of follow up research,…
A 257 patient New England Journal of Medicine study found microplastics in 58 percent of carotid plaques, with a 4.5 fold higher rate of heart attack, stroke, and death. A…
For decades, neuroscience taught that the adult human brain was a closed shop: every neuron you would ever own was already wired by the time you finished puberty. A wave…
A Swedish national cohort study of over 100,000 people published in The Lancet Psychiatry found that semaglutide use was associated with 44% lower depression risk, 38% lower anxiety, and 47%…
A Nature Communications study from UCLA found that severe narcolepsy destroys neurons in a second brain region previously overlooked, overturning a foundational assumption held for nearly 25 years and opening…
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