Healthcare Discovery MechanoAge breast cancer AI mechanical age risk showing cells measured in a microfluidic diagnostic platform
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First-in-Class Bispecific ADC Rewrites the Rules for Triple-Negative Breast Cancer at ASCO 2026

At ASCO 2026, izalontamab brengitecan became the first bispecific antibody-drug conjugate to improve both progression-free and overall survival in triple-negative breast cancer. Inside the EGFRxHER3 mechanism, the Phase 3 trial…

AI revealing hidden binding pockets in formerly undruggable proteins for drug discovery
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The Quiet Drug Discovery Revolution: How Protein Degraders Are Cracking the Undruggable Proteome in 2026

More than thirty targeted protein degraders are now in human trials, with the first Phase 3 readouts arriving in 2026. Inside the vepdegestrant breast cancer data, the BTK degrader race,…

GLP-1 drugs cancer risk reduction clinical research ASCO 2026 | Healthcare Discovery
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The Unexpected Cancer Shield: ASCO 2026 Data Shows GLP-1 Drugs Cut Advanced Tumor Progression by Up to 50%

A major study being presented this week at the American Society of Clinical Oncology’s annual meeting found that patients with early-stage cancer who took GLP-1 receptor agonists were 38 to…

HealthcareDiscovery.ai title card showing clinicians reviewing AI-assisted medical imaging for FDA AI medical devices guide
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The First Wave of AI-Designed Drugs Hits Human Trials: A 2026 Status Report on Insilico, Isomorphic, and Recursion

As of May 2026, more than 75 AI-discovered drugs are in human trials. Inside the Insilico IPF Phase 2 program, Isomorphic Labs partnerships with Novartis and Lilly, Recursion’s Phase 2…

Healthcare Discovery lipoprotein(a) RNA therapy cardiovascular risk 2026 showing inherited Lp(a) risk and RNA silencing in the liver
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Lipoprotein(a) and the Hidden Heart Risk Revolution: 60 Years After Discovery, Cardiology Gets Its First Real Drugs in 2026

Lipoprotein(a) is one of the most powerful inherited cardiovascular risk factors ever described, affecting roughly 1.4 billion people globally. After 60 years without a drug, three Phase 3 outcomes trials…

Scientists reviewing gene expression aging data in a DNA research laboratory | Healthcare Discovery
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Cracking the Undruggable Code: How Daraxonrasib Just Rewrote the Rules for Pancreatic Cancer Survival

A new KRAS-targeting oral drug called daraxonrasib has nearly doubled survival in metastatic pancreatic cancer, with median overall survival of 13.2 months versus 6.7 months on chemotherapy in the landmark…

Senolytic therapy targeting senescent zombie cells in aging tissue during 2026 longevity clinical trials
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Senolytics in 2026: How the Science of Killing Zombie Cells Reached Its First Human Proof of Concept

A decade of senolytic research is converging into something new. Inside the Mayo Clinic dasatinib quercetin work, the AFFIRM-LITE fisetin trial, Rubedo’s March 2026 Phase 1 readout of RLS-1496, and…

Healthcare Discovery lipoprotein(a) RNA therapy cardiovascular risk 2026 showing inherited Lp(a) risk and RNA silencing in the liver
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Lp(a) and Heart Disease 2026: The Genetic Risk Factor Statins Cannot Touch and the New Wave of Therapies That Could Change Cardiology

An estimated 1.4 billion people globally carry elevated lipoprotein(a), a genetically inherited cardiovascular risk factor that statins do not lower. Inside the biology of Lp(a), why the science went quiet…