A randomized controlled trial from the University of Nottingham has delivered a striking result: a simple, daily prebiotic fiber supplement reduced knee osteoarthritis pain in six weeks, rivaled the effects…
A landmark study from the Leibniz Institute on Aging identifies a specific membrane lipid as the upstream trigger for mitochondrial fragmentation — and shows that dietary intervention can reverse the…
ER-100 has entered an 18-person Phase 1 eye trial. Here is what partial epigenetic reprogramming has—and has not—shown in humans.
NAD+, the coenzyme that powers every cell, falls steadily as we age. Inside the biology of the decline, the CD38 and mitochondrial mechanisms driving it, what the NMN and nicotinamide…
A deep dive into neuroinflammageing and the 2025 to 2026 research showing the brain’s resident immune cells, the microglia, drive cognitive aging, and how scientists at Cedars-Sinai, UC Irvine, and…
A landmark 2026 Nature Aging study reveals why senescent cells resist the drugs designed to kill them: the toughest zombie cells keep their mitochondria pristine. Inside the senolytics reckoning, the…
A landmark Nature Communications study from Hebrew University of Jerusalem delivers the first causal genetic proof that a single gene trades early-life advantages for accelerated aging and cancer, confirming a…
Almost three decades after Makoto Kuro-o named the protein after the Greek Fate of life, UCSF’s Dena Dubal has launched the first human trial of klotho. Inside the cell biology,…
A landmark Nature study from Mass General Brigham analyzed 11,000+ gene expression profiles across four mammalian species and found that aging leaves the same molecular fingerprint in virtually every tissue…
A landmark study presented at Digestive Disease Week 2026 used autologous fecal microbiota transplant to restore a younger microbial fingerprint in aging mice, reversing core hallmarks of liver aging and…
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