Spermidine triggers autophagy, the cell’s recycling system, and a 20 year Austrian cohort linked higher dietary intake to roughly 5 fewer years of mortality. Inside the Frank Madeo Graz research,…
Revolution Medicines’ daraxonrasib achieved a median overall survival of 13.2 months versus 6.7 months for chemotherapy in previously treated metastatic pancreatic cancer, a 60 percent reduction in the risk of…
A decade of senolytic research is converging into something new. Inside the Mayo Clinic dasatinib quercetin work, the AFFIRM-LITE fisetin trial, Rubedo’s March 2026 Phase 1 readout of RLS-1496, and…
A decade after parabiosis lit up the longevity field, the science of young blood has matured into rigorous plasma exchange trials, recombinant rejuvenation factors, and a quietly revealing exercise literature….
The most anticipated longevity drug trial in a generation has delivered its full one-year results. Here is what rapamycin actually did to lean muscle, pain, biological age, and overall healthspan…
A UC Berkeley and City of Hope team published a landmark AI platform called MechanoAge in Lancet’s eBioMedicine that measures the physical stress-response of individual breast cells to identify cancer…
A Nobel laureate on its board. The world’s largest pharmaceutical company as a founding partner. And a scientific mission to build drugs that target aging itself. Inside Insilico Medicine’s Longevity…
More than 30 senolytic and senomorphic clinical trials are now active, spanning diabetic macular edema, pulmonary fibrosis, osteoarthritis, and frailty. Inside the science of zombie cells, the first-generation compounds from…
A two-dose nasal spray built from human neural stem cell-derived particles silenced the inflammation signals that drive cognitive decline, restored memory in aged mice, and is now being positioned for…
In 2026, mitochondria have moved from a footnote in biology textbooks to the central organelle of aging research. From urolithin A’s mitophagy revolution to new NAD+ trials, MOTS-c, and the…
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