For decades creatine was framed as a supplement for lifters. In 2026, new research on cognition, mood, bone density, and sarcopenia is repositioning creatine as a foundational tool for healthy…
In 2026, mitochondria have moved from a footnote in biology textbooks to the central organelle of aging research. From urolithin A’s mitophagy revolution to new NAD+ trials, MOTS-c, and the…
In 2026, cardiorespiratory fitness is the most validated longevity marker in medicine. From Cleveland Clinic mortality data to Ulrik Wisløff’s 4 by 4 intervals and Iñigo San Millán’s zone 2…
Discovered almost by accident in 1997 and named after the Greek fate that spins the thread of life, klotho is the longevity hormone that may connect kidney biology, cognitive aging,…
New 2026 research is reshaping longevity medicine through the gut. From Kenya Honda’s discovery of isoalloLCA in Japanese centenarians, to Patrice Cani’s Akkermansia muciniphila trials at UCLouvain, to the ARMOR…
Scientists at the 2nd World Congress on Targeting Longevity in Berlin delivered an uncomfortable verdict in April 2026: despite decades of discoveries, longevity science has stalled on clinical translation. The…
New 2026 research on myokines, the signaling proteins released by contracting muscle, shows why strength training is a cognitive intervention. Here is what the science reveals about irisin, cathepsin B,…
For decades, cardiac amyloidosis was a diagnosis cardiologists whispered and patients rarely heard. In 2026, tafamidis, acoramidis, RNA silencers, and a CRISPR gene editing therapy are transforming ATTR care and…
New glymphatic research reveals that deep slow wave sleep drives the brain’s nightly clearance of amyloid and tau, with 2026 data linking sleep architecture to long term dementia risk and…
Phase 3 trials of pelacarsen, olpasiran, lepodisiran, and the first oral Lp(a) drug muvalaplin are ending cardiology’s sixty year blind spot on lipoprotein(a), a genetically determined particle that silently elevates…
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