The most anticipated longevity drug trial in a generation has delivered its full one-year results. Here is what rapamycin actually did to lean muscle, pain, biological age, and overall healthspan…
A growing body of research from Bente Pedersen’s Copenhagen lab, Henriette van Praag at Florida Atlantic, and the 2024 to 2026 wave of muscle-brain studies is reframing skeletal muscle as…
A landmark 2026 Nature Communications study delivers the first direct human evidence that sleep-driven glymphatic clearance pushes amyloid beta and tau out of the brain and into the bloodstream. Inside…
A 60,977-person UK Biobank study found that sleep regularity predicts all-cause mortality more powerfully than sleep duration. Inside the science of the Sleep Regularity Index, social jet lag, slow-wave sleep,…
A 122,007-patient Cleveland Clinic study found that low cardiorespiratory fitness carried a hazard ratio for all-cause mortality of 5.04, higher than smoking, diabetes, hypertension, and end-stage kidney disease combined. Inside…
Three convergent lines of 2025 to 2026 research, including the Janelia colanic acid breakthrough, Akkermansia muciniphila clinical trials, and the centenarian microbiome signature, are reframing the gut as a programmable…
A Nobel laureate on its board. The world’s largest pharmaceutical company as a founding partner. And a scientific mission to build drugs that target aging itself. Inside Insilico Medicine’s Longevity…
Lp(a) affects one in five adults worldwide yet has had no targeted therapy for sixty years. In 2026, four Phase 3 trials including HORIZON, OCEAN(a)-Outcomes, ACCLAIM-Lp(a), and a new oral…
Insilico Medicine has formed the industry’s first Longevity Board, chaired by Eli Lilly’s Group VP of Molecular Discovery and featuring Nobel laureate Michael Levitt. Inside the AI strategy, dual-purpose targets,…
Zone 2 training has become the most talked about protocol in longevity circles, from Peter Attia to Iñigo San-Millán. Here is what the mitochondrial science actually says about low-intensity cardio,…
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