Thyroid autoimmune disease visual showing clonal B cells with somatic mutations disabling immune checkpoints
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The Hashimoto’s Breakthrough: Somatic Mutations and the New Model of Autoimmune Disease

A landmark Nature study finds that Hashimoto’s thyroiditis is driven in part by acquired somatic mutations that disable the immune system’s brakes. A new model of autoimmune disease is taking…

AI longevity board concept showing drug discovery pathways and hallmarks of aging biomarkers
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The First Longevity Board: How Insilico Medicine Is Using AI to Target the Biology of Aging Itself

Insilico Medicine has formed the industry’s first Longevity Board, chaired by Eli Lilly’s Group VP of Molecular Discovery and featuring Nobel laureate Michael Levitt. Inside the AI strategy, dual-purpose targets,…

Healthcare Discovery Adrian Woolfson Future of Species artificial biological intelligence image showing ancestral genome writing and modern synthetic biology
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Authoring Life by Means of Artificial Biological Intelligence: On the Future of Species by Adrian Woolfson

About ten thousand years ago, a group of Neolithic farmers in the Balsas River Basin of Mexico began writing a genome. They did not know it. The crop they produced,…

Healthcare Discovery Adrian Woolfson reading DNA and writing medicine through synthetic genomics
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How Adrian Woolfson Is Helping Medicine Move From Reading DNA to Writing It

Adrian Woolfson trained under a Nobel laureate at Cambridge, ran global oncology programs at the world’s largest pharmaceutical companies, and led research and development at Sangamo Therapeutics during the first…