A landmark study presented at Digestive Disease Week 2026 used autologous fecal microbiota transplant to restore a younger microbial fingerprint in aging mice, reversing core hallmarks of liver aging and…
Two landmark studies published this month are rewriting the cellular biology of aging, revealing that the very cells once viewed as purely destructive may hold the most precise key yet…
First documented by Makoto Kuro-o in a 1997 Nature paper, the Klotho hormone has spent thirty years quietly accumulating one of the deepest evidence bases in aging biology. With Phase…
The future of longevity may not begin with a miracle drug. It may begin with learning how to read the body’s signals: strength, oxygen capacity, sleep, metabolism, inflammation, recovery, and…
Scientists at the Institute for Bioengineering of Catalonia and West China Hospital engineered supramolecular nanoparticles that cleared 50 to 60 percent of amyloid-beta from Alzheimer’s mice within one hour, restored…
Iñigo San Millán’s mitochondrial research, Peter Attia’s popularization, and Stephen Seiler’s polarized training data have converged into a new consensus: the easy, conversational pace most people skip may be the…
A 2021 Nature paper from Kenya Honda’s lab at Keio University identified a chemically distinct bile acid called isoalloLCA in the stool of Japanese centenarians. Five years of follow up…
University of Rochester researchers transferred the naked mole rat’s longevity gene, nmrHAS2, into mice and produced animals with 34% less cancer, lower inflammaging markers, healthier guts, and a 4.4% longer…
A landmark Science study from Israel’s Weizmann Institute reveals that genetics accounts for roughly 50% of variation in human lifespan, more than double previous estimates, upending decades of thinking about…
A 2018 JAMA Network Open study of 122,007 patients found that low cardiorespiratory fitness was a stronger predictor of mortality than smoking, diabetes, or coronary artery disease. Inside the Mandsager,…
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