A growing body of research from Bente Pedersen’s Copenhagen lab, Henriette van Praag at Florida Atlantic, and the 2024 to 2026 wave of muscle-brain studies is reframing skeletal muscle as…
A landmark 2026 Nature Communications study delivers the first direct human evidence that sleep-driven glymphatic clearance pushes amyloid beta and tau out of the brain and into the bloodstream. Inside…
A UC Berkeley and City of Hope team published a landmark AI platform called MechanoAge in Lancet’s eBioMedicine that measures the physical stress-response of individual breast cells to identify cancer…
🧬 SuperAgers Grow 2.5x More New Neurons Than Their Peers — Northwestern researchers found that exceptional cognitive aging in adults over 80 is driven by dramatically elevated neurogenesis, offering a new biological target for brain longevity therapies. 🦠 Hidden Gut Virus Linked to Colorectal Cancer Risk — A previously unknown bacteriophage inside common gut bacteria appears at significantly higher rates in colorectal cancer patients, pointing to a new microbiome-based cancer screening opportunity. 💊 Novo Nordisk and OpenAI Join Forces for Drug Discovery — The partnership deploys AI across R&D, manufacturing, and commercial operations as pharmaceutical giants accelerate the race to AI-native drug pipelines. 🍽️ Fasting's Lifespan Benefit Lives in the Refeeding, Not the Fast Itself — UT Southwestern researchers traced the 60%-plus lifespan extension of fasting to the metabolic reset during refeeding, reframing how intermittent fasting protocols should be designed and studied. ⚡ Muscle Power Outperforms Strength as a Mortality Predictor — Mayo Clinic researchers found that the ability to generate force quickly is a stronger predictor of all-cause mortality than raw strength, arguing for power training as a core longevity medicine intervention.
A 60,977-person UK Biobank study found that sleep regularity predicts all-cause mortality more powerfully than sleep duration. Inside the science of the Sleep Regularity Index, social jet lag, slow-wave sleep,…
Four diseases will kill almost everyone you love. They are not random. They are not inevitable. And they are coming. The framework, science, and tools for the fight ahead.
A 122,007-patient Cleveland Clinic study found that low cardiorespiratory fitness carried a hazard ratio for all-cause mortality of 5.04, higher than smoking, diabetes, hypertension, and end-stage kidney disease combined. Inside…
Three convergent lines of 2025 to 2026 research, including the Janelia colanic acid breakthrough, Akkermansia muciniphila clinical trials, and the centenarian microbiome signature, are reframing the gut as a programmable…
A Nobel laureate on its board. The world’s largest pharmaceutical company as a founding partner. And a scientific mission to build drugs that target aging itself. Inside Insilico Medicine’s Longevity…
A capstone essay closing our series on the Mosaic Body. The new science of somatic mutation, clonal expansion, and mosaic aging is more than an interesting development in molecular biology….
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